ZOFRAN to treat morning sickness
Zofran is used to prevent nausea and vomiting that may be caused by chemotherapy or radiation in treating cancer. It also has been used off-label by pregnant women to treat morning sickness and may be linked to to birth defects in babies including:
- Cleft palate – malformation in early pregnancy where there is an split or opening in the roof of the mouth
- Cleft lip – malformation early in pregancy where the two side of the upper lip has a gap in the skin
- Atrial Septal Defect (ASD) – a hole in between the two upper chambers of the heart
- Ventricular Septal Defect (VSD) – a hole in between the two lower chambers of the heart
- Other congenital heart defects.
CONTRAINDICATIONS of Zofran:
- Hypersensitivity to other selective 5-HT3 receptor antagonists
- Co administration of Apomorphine – Causes profound hypotension and loss of consciousness
- Serotonin syndrome – Adverse drug interaction
- Avoid usage in patient with congenital QT syndrome
ZOFRAN MUTLIDISTRICT LITIGATION
Lawsuits alleging birth defects from Zofran have been consolidated into a multidistrict litigation (MDL) before Judge Dennis F. Saylor, IV, in the District of Massachusetts. As of December 1, 2015, over 220 lawsuits have been transferred to the MDL.
Court Records:
The zofran lawsuits filed include these allegations:
- That Glaxo had a legal obligation to ensure that Zofran was safe before releasing it, and failed to determine its safety risks before promoting it.
- That the company failed to adequately warn the public and medical communities about the risk of Zofran side effects.
- That Glaxo marketed Zofran as a safe treatment for morning sickness and hyperemiesis gravidarum even though it had not been approved by the FDA for this use.
- That Glaxo misrepresented animal studies indicating that Zofran was safe, when in reality the studies showed abnormal bone growth and signs of toxicity.
- That Glaxo failed to properly analyze all data and safety information regarding Zofran use in pregnant women.
- That the company manufactured a defective drug.
- That the company falsely claimed it was safe for pregnant woman.
The Ruth Law Team is currently investigating birth injury claims induced by Zofran. If you or a loved one has taken Zofran for morning sickness and had a baby with a birth detect, contact the experience lawyers now at 1-888-783-8378 for a free consultation.